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Ukr. Bioorg. Acta 2020, Vol. 15, N1, 42-46.

Investigation of the extract's composition of Viper's bugloss (Echium vulgare)

Anna R. Kapusterynska, Vira R. Hamada, Anna S. Krvavych, Roksolana T. Konechna, Maria S. Kurka, Volodymyr P. Novikov

Lviv Polytechnic National University, 79013 Lviv, Ukraine
Å-mail: tbsfb.dept@lpnu.ua

ABSTRACT
The characteristics of Viper's bugloss (Echium vulgare) plant, its pharmacological properties, and extracts’ composition are presented in this study. Results of the literature analysis, data on the biologically active compounds and areas of use of this medicinal plant are summarized. Viper's bugloss (Echium vulgare) is a species of flowering plant in the borage family Boraginaceae. It is native to most of Europe as well as western and central Asia. Viper's bugloss (Echium vulgare) is a plant that has been utilized as food (honey), medicine, a poison, an oil, and as a dye and tannin-producing ornamental plant. Viper's bugloss (Echium vulgare) is especially rich in pyrrolizidine alkaloids, flavonoids, phenolcarboxylic acids, sterones and naphthoquinones. In traditional medicine, Viper's bugloss (Echium vulgare) is utilized as exhilarant and a mood stimulant. That is why one of the possible uses of this plant is considered to be treatment of depressive states. Like most representatives of Boraginaceae family, it has been insufficiently studied. No previous work quantifying flavonoids content of aerial parts of Viper's bugloss (Echium vulgare) growing in Ukraine has been presented. Continuing the studies of this species, the aqueous and ethanolic extracts from Viper's bugloss (Echium vulgare) aerial parts were obtained and their phytochemical composition was investigated. For the first time, the qualitative analysis of Viper’s bugloss’s extracts in relation to biologically active compounds and the quantitative analysis of flavonoids by aluminum chloride spectrophotometric method are reported. The experimental results indicated that the total flavonoid concentration was 2.59% in extract. The maximum yield of extractives was found to be 16%. The obtained research data will be used in future investigations.

KEYWORDS
Viper's bugloss (Echium vulgare); biologically active substances; flavonoids; depression.

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