Ukr. Bioorg. Acta 2020, Vol. 15, N1

hpps://doi.org/10.15407/bioorganica2020.01

CONTENTS

Kostyantyn V. Turov, Оleg P. Mitiukhin, Svitlana A. Chumachenko, Vladimir S. Zyabrev, Volodymyr S. Brovarets
Anticancer evaluation of di- and trifunctional substituted 1,3-thiazoles

2

Maryna Yu. Zhuravlova, Nataliya V. Obernikhina, Stepan G. Pilyo, Maryna V. Kachaeva, Oleksiy D. Kachkovsky, Volodymyr S. Brovarets
In silico binding affinity studies of phenyl-substituted 1,3-oxazoles with protein molecules

12

Oksana V. Muzychka, Oleksandr L. Kobzar, Oleh V. Shablykin, Volodymyr S. Brovarets, Andriy I. Vovk
5-Substituted N-(9H-purin-6-yl)-1,2-oxazole-3-carboxamides as xanthine oxidase inhibitors

20

Roman N. Vydzhak, Maryna V. Kachaeva, Stepan G. Pilyo, Viktoriia S. Moskvina, Olga V. Shablykina, Andriy V. Kozytskiy, Volodymyr S. Brovarets
Three-component cyclization as an approach to a combinatorial library of 2H-spiro-[chromeno[2,3-c]pyrrole-1,3'-indoline]-2',3,9-triones

26

Valentina G. Kostina, Inna V. Alexeeva, Nadia A. Lysenko, Valentina V. Negrutska, Igor Y. Dubey
Cationic carboxamide derivatives of tricyclic heteroaromatic compounds: synthesis and preliminary evaluation of antiproliferative activity

34

Anna R. Kapusterynska, Vira R. Hamada, Anna S. Krvavych, Roksolana T. Konechna, Maria S. Kurka, Volodymyr P. Novikov
Investigation of the extract's composition of Viper's bugloss (Echium vulgare)

42

Volodymyr V. Tkach, Marta V. Kushnir, Yana G. Ivanushko, Svitlana M. Lukanova, Silvio C. de Oliveira, Petro I. Yagodynets
The mathematical description of dopamine electrochemical oxidation, accompanied by its chemical and electrochemical polymerization

47

Volodymyr V. Tkach, Marta V. Kushnir, Yana G. Ivanushko, Silvio C. de Oliveira, Olga V. Luganska, Petro I. Yagodynets, Zholt O. Kormosh
Theoretical evaluation of electroanalitical determination of diazoline (mebhydrolin) on a polymer electrode

53